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Showing posts with label ARWR. Show all posts
Showing posts with label ARWR. Show all posts

Thursday, October 4, 2018

=Arrowhead (ARWR) enters into license and collaboration agreement with Janssen Pharmaceuticals (JNJ)



Arrowhead enters into license and collaboration agreement with Janssen Pharmaceuticals (JNJ) to develop and commercialize ARO-HBV, will receive $175 mln as an upfront payment & $75 mln investment at $23.00/share 
In addition, Arrowhead entered into a research collaboration and option agreement with Janssen to potentially collaborate for up to three additional RNA interference (RNAi) therapeutics against new targets to be selected by Janssen. The transactions have a combined potential value of over $3.7 billion for Arrowhead.
  • Under the terms of the agreement, Arrowhead will receive $175 million as an upfront payment. Separately, Johnson & Johnson Innovation -- JJDC, Inc. (JJDC) will make a $75 million equity investment in Arrowhead at a price of $23.00 per share of Arrowhead common stock.
  • Arrowhead is eligible to receive up to approximately $1.6 billion in milestone payments for the HBV license agreement, including a $50 million milestone payment linked to a Phase 2 study. Arrowhead is also eligible to receive approximately $1.9 billion in option and milestone payments for the collaboration agreement related to up to three additional targets. Arrowhead is further eligible to receive tiered royalties up to mid teens on product sales.

Thursday, September 6, 2018

-=Arrowhead Pharmaceuticals (ARWR) : upbeat trial data prompts analyst upgrade


Upbeat results of the company's treatment for chronic hepatitis B prompted an upgrade at B. Riley FBR. The company said clinical data for ARO-HBV demonstrated that three monthly doses led to a "maximum reduction" in circulating HBV surface antigen. Analyst Madhu Kumar at B. Riley FBR followed by raising the rating to buy from neutral, and lifting the stock price target to $19. "While early, we believe these findings provide clinical proof of concept for ARWR's current HBV RNAi franchise, through multi-log suppression of hepatitis B surface antigen (HBsAg)," Kumar wrote in a note to clients.